Welcome to the Qi lab
We are in the Department of Physiology & Biophysics, Case Western Reserve University School of Medicine
Our laboratory focuses on understanding the roles of mitochondrial quality control in neurodegenerative diseases. We use the combination of unbiased proteomics and genomics, cellular and molecular biology, genetic manipulation in vitro and in vivo, patient iPS cells-derived cell culture and diseased animals to investigate the fundamental mechanisms and pathways by which mitochondrial impairment contributes to neurodegeneration. We also utilize rationally designed peptide inhibitors of protein-protein interactions and high throughput screening approach to developing “mitochondrial medicine” as therapeutic strategies for treating neurodegenerative diseases.